Spedra contains the active substance avanafil. It belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. Spedra is a treatment for adult men suffering from erectile dysfunction (also known as impotence). This is when you cannot get, or keep a hard, erect penis suitable for sexual activity.
Spedra works by helping the blood vessels in your penis to relax. This increases the blood flow into your penis, helping it stay hard and erect when you get sexually excited. Spedra does not cure your condition.
It is important to note that Spedra only works if you are sexually stimulated. You and your partner will still need to use foreplay to get ready for sex – just as you would if you were not taking a medicine to help you.
Spedra will not help you if you do not have erectile dysfunction. Spedra is not for women.
Uses / Instructions
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
The recommended dose is a 100 mg tablet, as needed. You should not take Spedra more than once a day. You could have been given the dose of one 200 mg tablet if your doctor has decided that the 100 mg dose was too weak for you, or the dose of one 50 mg tablet if your doctor has decided that the 100 mg tablet was too strong for you. Dose adjustments can also be required if Spedra is used together with certain other medicines. If you are taking a medicine such as erythromycin, amprenavir, aprepitant, diltiazem, fluconazole, fosamprenavir or verapamil (‘moderate CYP3A4 inhibitors’) the recommended dose of Spedra is a 100 mg tablet, with an interval of at least 2 days between doses.
You should take Spedra about 30 minutes (50 mg) or approximately 15 to 30 minutes (100 mg and 200 mg) before you have sexual intercourse. Remember that Spedra will only help you to get an erection if you are sexually stimulated.
Spedra can be taken with or without food; if taken with food, it may take longer to work.
Talk to your doctor or pharmacist before taking Spedra:
- If you have heart trouble. It may be risky for you to have sexual intercourse
- If you suffer from priapism, that is a persistent erection lasting 4 hours or more. This can happen in men with conditions like sickle cell disease, multiple myeloma or leukaemia.
- If you have a physical condition that affects the shape of your penis (such as angulation, Peyronie’s disease or cavernosal fibrosis)
- If you have any bleeding disorder or active peptic ulceration.
If any of the above apply to you talk to your doctor or pharmacist before taking Spedra. Check with your doctor or pharmacist if you are not sure.
Problems with your sight or hearing
Some men taking medicines like Spedra have had problems with their sight and hearing. Read the patient information leaflet for more information.
Common (may affect up to 1 in 10 people)
- nasal congestion
Uncommon (may affect up to 1 in 100 people)
- feeling dizzy
- feeling sleepy or very tired
- sinus congestion
- back pain
- hot flush
- feeling out of breath when you exert yourself
- heartbeat changes seen on a heart tracing (ECG)
- increased heart beat
- feeling your heartbeat in your chest (palpitations)
- indigestion, feeling or being sick to your stomach
- blurry vision
- raised liver
For a full list the patient information leaflet