Description
Ramipril capsules contain a medicine called ramipril. This belongs to a group of medicines called ACE inhibitors
(Angiotensin Converting Enzyme Inhibitors).
Ramipril capsules works by:
- Decreasing your body’s production of substances that could raise your blood pressure
- Making your blood vessels relax and widen
- Making it easier for your heart to pump blood around your body
Ramipril capsules can be used:
- To treat high blood pressure (hypertension)
- To reduce the risk of you having a heart attack or stroke
- To reduce the risk or delay the worsening of kidney problems (whether or not you have diabetes)
- To treat your heart when it cannot pump enough blood to the rest of your body (heart failure)
- As treatment following heart attack (myocardial infarction) complicated with heart failure
Uses / Instructions
Take as directed by your Doctor usually ONE capsule daily at the same time of day each day.
Warnings
Talk to your doctor or pharmacist before taking Ramipril capsules:
- If you have heart, liver or kidney problems
- If you have lost a lot of body salts or fluids (through being sick (vomiting), having diarrhoea, sweating more than usual, being on a low salt diet, taking diuretics (water tablets) for a long time or having had dialysis)
- If you are going to have treatment to reduce your allergy to bee or wasp stings (desensitization)
- If you are going to receive an anaesthetic. This may be given for an operation or any dental work. You
may need to stop your Ramipril capsules treatment one day beforehand; ask your doctor for advice
- If you have high amounts of potassium in your blood (shown in blood test results)
- If you are taking medicines or have conditions which may decrease sodium levels in your blood. Your doctor may carry out regular blood tests, particularly for checking the levels of sodium in your blood especially if you are elderly.
- If you are taking medicines that may increase the risk of angioedema, a serious allergic reaction, such as mTOR inhibitors (e.g. temsirolimus, everolimus, sirolimus, vildagliptin neprilysin (NEP) inhibitors (such as racecadontril) or sacubitril/valsartan. For sacubitril/valsartan, see section 2 “Do not take Ramipril
capsule”.
- If you have collagen vascular disease such as scleroderma or systemic lupus erythematosus
- You must tell your doctor if you think that you are (or might become) pregnant. Ramipril is not recommended in the first 3 months of pregnancy and may cause serious harm to your baby after 3 months of pregnancy, see section below on “Pregnancy and breast feeding”
- If you are taking any of the following medicines used to treat high blood pressure:
– an angiotensin II receptor blocker (ARBs) (also known as sartans – for example valsartan, telmisartan, irbesartan), in particular if you have diabetes-related kidney problems.
– aliskiren
Your doctor may check your kidney function, blood pressure, and the amount of electrolytes (e.g. potassium) in your blood at regular intervals. See also information under the heading “Do not take Ramipril capsules”
Side Effects
Common (may affect up to 1 in 10 people)
- Headache or feeling tired
- Feeling dizzy. This is more likely to happen when you start taking Ramipril capsules or start taking a higher dose
- Fainting, hypotension (abnormally low blood pressure), especially when you stand or sit up quickly
- Dry tickly cough, inflammation of your sinuses (sinusitis) or bronchitis, shortness of breath
- Stomach or gut pain, diarrhoea, indigestion, feeling or being sick
- Skin rash with or without raised area
- Chest pain
- Cramps or pain in your muscles
- Blood tests showing more potassium than usual in your blood.
Uncommon (may affect up to 1 in 100 people)
- Balance problems (vertigo)
- Itching and unusual skin sensations such as numbness, tingling, pricking, burning or creeping on your skin (paraesthesia)
- Loss or change in the way things taste
- Sleep problems
- Feeling depressed, anxious, more nervous than usual or restless
- Blocked nose, difficulty breathing or worsening of asthma
- A swelling in your gut called “intestinal angioedema” presenting with symptoms like abdominal pain, vomiting and diarrhoea
- Heartburn, constipation or dry mouth
- Passing more water (urine) than usual over the day
- Sweating more than usual
- Loss or decrease of appetite (anorexia)
- Increased or irregular heartbeats
- Swollen arms and legs. This may be a sign of your body holding onto more water than usual
- Flushing
- Blurred vision
- Pain in your joints
- Fever
- Sexual inability in men, reduced sexual desire in men or women
- An increased number of certain white blood cells (eosinophilia) found during a blood test
- Blood tests showing changes in the way your liver, pancreas or kidneys are working
Ingredients
The active ingredient is Ramipril.
For a list of other ingredients see the patient information leaflet of the medicine you receive as dfifferent brands have different other ingredients.
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