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Cilique is a combined hormonal contraceptive pill (‘the Pill’). You take it to stop getting pregnant.

Information Leaflet


This contraceptive contains two types of female sex hormones, oestrogen and progestogen. These hormones
prevent an egg being released from your ovaries so you can’t get pregnant.

Also, Cilique makes the fluid (mucus) in your cervix thicker which makes it more difficult for sperm to enter the
womb. Cilique is a 21-day Pill – you take one each day for 21 days, followed by 7 days when you take no pills.

Uses / Instructions

Take Cilique every day for 21 days

Cilique comes in a strip of 21 pills, each marked with a day of the week.
• Take your pill at the same time every day.
• Start by taking a pill marked with the correct day of the week.
• Follow the direction of the arrows on the strip. Take one pill each day.
• Swallow each pill whole, with water if necessary. Do not chew the pill.

Then have seven pill-free days

See patient information leaflet for full details.


Do not take Cilique if any of the following applies to you:

• If you have (or have ever had) a blood clot in a blood vessel of your legs (deep vein thrombosis, DVT), your lungs (pulmonary embolism, PE) or other organs
• If you know you have a disorder affecting your blood clotting (for instance, protein C deficiency, protein S deficiency, antithrombin-III deficiency, Factor V Leiden or
antiphospholipid antibodies)
• If you need an operation or if you are off your feet for a long time (see Section 2.3 ‘The Pill and blood clots’)
• If you have ever had a heart attack or stroke
• If you have (or have ever had) angina pectoris (a condition that causes severe chest pain which may be a first sign of a heart attack) or transient ischaemic attack (TIA -temporary stroke symptoms)
• If you have any of the following diseases that may increase your risk of a clot in the arteries:
– severe diabetes with blood vessel damage
– very high blood pressure
– very high level of fat in the blood (cholesterol or triglycerides)
– a condition called hyperhomocysteinaemia
• If you have cancer affected by sex hormones – such as some cancers of the breast or womb lining
• If you have (or have ever had) a type of migraine called ‘migraine with aura’
• If you have breast or liver cancer
• If you have or have recently had a severe liver disease
• If you have hepatitis C and are taking antiviral drug combinations containing paritaprevir/ritonavir, ombitasvir, and dasabuvir (see also in section Other medicines and Cilique).
• If you are allergic (hypersensitive) to any of the ingredients in Cilique.
• If you have vaginal bleeding that has not been explained by your doctor

Side Effects

• increased blood pressure (uncommon – may affect up to 1 in 100 people)
• fits (convulsions) (frequency not known)
• hives (urticaria) (uncommon – may affect up to 1 in 100 people), swelling of the face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing.

These may be signs of allergy.

See patient information leaflet for full details.


The active substances:

250 micrograms of norgestimate and 35 micrograms of ethinylestradiol.

Other ingredients:

maize starch, lactose, magnesium stearate (E470b), indigo carmine (E132).


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